Alfaxalone Dosing for Dogs and Cats By Weight
Important Safety Information
Always titrate the dose according to the patient response. Monitor vital signs continuously during administration.
Use with caution in animals with cardiovascular disease, respiratory compromise, or hepatic impairment.
Reference Source
Saunders Handbook of VETERINARY DRUGS, Page 44-45
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Standard Dosage Guidelines
Small Animal Dosage
| Species | Route | Condition | Dosage | Frequency |
|---|---|---|---|---|
| Dogs | IV | No preanesthetic | 1.5-4.5 mg/kg | Induction dose IV over 60 seconds |
| With preanesthetic | 0.2-3.5 mg/kg | Induction dose IV over 60 seconds | ||
| Constant-rate infusion | N/A | 6-7 mg/kg/hour | With other anesthetic agents | |
| Note: Generally 1-1.2 mg/kg (up to 2 mg/kg) for each 10 minutes of anesthesia | ||||
| Cats | IV | No preanesthetic | 2.2-9.7 mg/kg | Induction dose IV over 60 seconds |
| With preanesthetic | 1-10.8 mg/kg | Induction dose IV over 60 seconds | ||
| Constant-rate infusion | N/A | 7-10 mg/kg/hour | After loading dose of 1.7 mg/kg IV | |
| Note: Generally 1-1.3 mg/kg IV (up to 5 mg/kg) followed by sequential doses of 2 mg/kg as needed | ||||
Large Animal Dosage
| Species | Route | Dosage | Frequency |
|---|---|---|---|
| Large Animals | N/A | No large animal doses are available | N/A |