Amiodarone Hydrochloride Dosing for Dogs, Cats, Horses By Weight
Important Safety Information
For Boxer or Doberman breeds: Doses as high as two times these rates have been administered, but with a higher risk of toxicity.
IV administration should be done slowly over 10 minutes. Use with caution due to risk of adverse effects.
Oral absorption in horses is low and inconsistent and has not been recommended.
Reference Source
Saunders Handbook of VETERINARY DRUGS, Page 57-59
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Standard Dosage Guidelines
Small Animal Dosage
| Species | Condition | Route | Dosage | Frequency |
|---|---|---|---|---|
| Dogs | Ventricular arrhythmias | PO | 10-15 mg/kg | q12h for 1 week, then 5-7.5 mg/kg q12h for 2 weeks, followed by maintenance dose of 7.5 mg/kg q24h |
| Refractory arrhythmias | PO | 25 mg/kg | q12h for 4 days, followed by 25 mg/kg q24h | |
| Atrial fibrillation | PO | 15 mg/kg loading dose | for 5 days, followed by 10 mg/kg per day thereafter | |
| Boxer or Doberman | PO | 200 mg per dog | q12h for 1 week, followed by 200 mg once daily thereafter | |
| Injection | IV | 5 mg/kg | Slowly IV over 10 minutes | |
| Cats | No dose has been reported for cats | |||
Large Animal Dosage
| Species | Condition | Route | Dosage | Frequency |
|---|---|---|---|---|
| Horses | Atrial fibrillation | IV | 5 mg/kg/hr for 1 hour, followed by 0.83 mg/kg/hr for 23 hours | IV infusion |