Atipamezole Hydrochloride Dosing for dogs, Cats, Horses By Weight
Important Safety Information
Inject the same volume as used for dexmedetomidine or medetomidine.
For horses: Used to reverse detomidine sedation. Do not exceed 0.15 mg/kg IV.
Use with caution in animals with cardiovascular disease or respiratory conditions.
Reference Source
Saunders Handbook of VETERINARY DRUGS, Page 84-85
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Standard Dosage Guidelines
Small Animal Dosage
| Species | Route | Dosage | Frequency |
|---|---|---|---|
| Dogs & Cats | IM, IV | 0.32 mg/kg (≤4 kg) | Single dose |
| IM, IV | 0.23 mg/kg (≤11 kg) | Single dose | |
| IM, IV | 0.14 mg/kg (>11 kg) | Single dose |
Large Animal Dosage
| Species | Route | Dosage | Frequency |
|---|---|---|---|
| Horses | IV | 0.06-0.15 mg/kg | Single dose (detomidine reversal) |
Dosage Note
Inject the same volume as used for dexmedetomidine or medetomidine. The range of doses (IM or IV) is 0.32 mg/kg for small animals (4 kg, or 8.8 pounds), 0.23 mg/kg for medium-sized animals (11 kg, or 24 pounds), and up to 0.14 mg/kg for large-sized animals (45 kg or 100 pounds).
Horses: The dose used in horses is 60-80 mcg/kg (0.06-0.08 mg/kg) IV, but has ranged up to 150 mcg/kg (0.15 mg/kg). Typically, 100 mcg/kg (0.1 mg/kg) IV is used to reverse detomidine.