Azathioprine Dosing for Dogs, Cats, Horses By Weight
Important Safety Information
Cats are particularly sensitive to bone marrow-suppressing effects of azathioprine. Use with extreme caution in cats and monitor carefully.
Always monitor complete blood counts during therapy. Adjust doses based on clinical response and laboratory monitoring.
Reference Source
Saunders Handbook of VETERINARY DRUGS, Page 92-93
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Standard Dosage Guidelines
Small Animal Dosage
| Species | Dosage | Frequency | Notes |
|---|---|---|---|
| Dogs | 2 mg/kg PO initially 0.5-1 mg/kg PO maintenance |
q24h initially, then q48h | Doses as high as 1.5 mg/kg q48h PO have been used with prednisolone |
| Cats (use cautiously) | 0.3 mg/kg PO | q24h initially, adjust to q48h | Cats are sensitive to bone marrow-suppressing effects. Tablet size may require careful compounding |
Large Animal Dosage
| Species | Dosage | Frequency | Notes |
|---|---|---|---|
| Horses | 3 mg/kg PO | q24h |