Cloprostenol Sodium Dosing for Dogs, Cats, Horses, Cattle By Weight
Important Safety Information
For dogs: Side effects are lower with 1 mcg/kg dose. Can be administered with cabergoline (Galastop) 5 mcg/kg oral q24h on days 1 through 7 of treatment.
For horses: To induce premature labor in the last 2-4 weeks of pregnancy, administer two doses 30 minutes apart (oxytocin also is used for this indication).
Reference Source
Saunders Handbook of VETERINARY DRUGS, Page 205-207
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Standard Dosage Guidelines
Small Animal Dosage
| Species | Route | Dosage | Frequency |
|---|---|---|---|
| Dogs | SQ | 1-2.5 mcg/kg | Once daily for 4-5 days, starting day 25 after mating |
| SQ | 1 mcg/kg | q48h SQ with bromocriptine | |
| Cats | SQ | 5 mcg/kg | Once daily SQ for 3 days |
Large Animal Dosage
| Species | Route | Dosage | Frequency |
|---|---|---|---|
| Horses | IM | 500 mcg per horse | Repeated every 12 hours if needed |
| Cattle | IM | 500 mcg | Once, repeated again 11 days after first injection |