Cosyntropin Dosing for Dogs, Cats, Horses, Foals By Weight
Important Information
Maximum dose for dogs should be 250 mcg (1 vial).
ACTH stimulation test is not recommended as a reliable test in horses.
Reference Source
Saunders Handbook of VETERINARY DRUGS, Page 215-216
Weight Unit Converter ▲
Weight Unit Converter ▼
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Standard Dosage Guidelines
Small Animal Dosage
| Species | Route | Dosage | Protocol |
|---|---|---|---|
| Dogs | IV, IM | 5 mcg/kg (max 250 mcg) Weight brackets: <5 kg: 25 mcg 5-10 kg: 50 mcg 10-15 kg: 75 mcg 15-20 kg: 100 mcg 20-25 kg: 125 mcg 25-30 kg: 150 mcg 30-40 kg: 200 mcg 40-50 kg: 225 mcg >50 kg: 250 mcg |
Response test: Collect pre-cosyntropin sample and inject dose IV or IM, collect post-sample at 30 and 60 minutes or one sample at 60 minutes |
| Cats | IV, IM | 125 mcg per cat | Response test: Collect pre-cosyntropin sample and inject 125 mcg per cat IV or IM, collect post-sample at 60 and 90 minutes after IV administration or at 30 and 60 minutes after IM administration |
Large Animal Dosage
| Species | Route | Dosage | Protocol |
|---|---|---|---|
| Horses | IV | 0.1 mcg/kg | Produces maximum adrenal stimulation, with peak cortisol concentration in 30-90 minutes. Not recommended as a reliable test in horses |
| Foals | IV | 0.25 mcg/kg | ACTH Stimulation test: Peak cortisol occurs at 20-30 minutes |