Cyclosporine, Cyclosporin A Dosing for Dogs, Cats, Horses By Weight
Important Safety Information
For immune suppression associated with organ transplantation in dogs, doses should be higher (7-10 mg/kg q12h PO).
For cats undergoing organ transplantation, doses should be higher (3-5 mg/kg q12h PO).
Administer with food to improve absorption and reduce gastrointestinal upset.
Reference Source
Saunders Handbook of VETERINARY DRUGS, Page 220-223
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Standard Dosage Guidelines
Small Animal Dosage
| Species | Route | Dosage | Frequency | Notes |
|---|---|---|---|---|
| Dogs | PO | 3-7 mg/kg/day | Daily | Typical starting dose: 5 mg/kg/day |
| 5-8 mg/kg | q12h | Perianal fistulas and immune-mediated diseases | ||
| 7-10 mg/kg | q12h | Organ transplantation | ||
| 5 mg/kg | q12h initially | Inflammatory bowel disease | ||
| Cats | PO | 7.5 mg/kg | Daily | May reduce to every other day or twice weekly |
| 3-5 mg/kg | q12h | Organ transplantation |
Large Animal Dosage
| Species | Route | Dosage | Frequency | Notes |
|---|---|---|---|---|
| Horses | Ocular | 0.2% | As directed | Only local ocular administration reported |