Cytarabine Dosing for Dogs, Cats By Body Surface Area
Important Safety Information
Cytarabine is a potent chemotherapeutic agent with significant side effects including myelosuppression, gastrointestinal toxicity, and neurotoxicity.
Use should be restricted to veterinarians experienced with chemotherapy protocols. Monitor blood counts regularly during treatment.
Reference Source
Saunders Handbook of VETERINARY DRUGS, Page 225-226
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Standard Dosage Guidelines
Small Animal Dosage
| Species | Condition | Dosage | Frequency/Route |
|---|---|---|---|
| Dogs | Cancer Protocols | 100-150 mg/m² once daily or 50 mg/m² twice daily |
4 days IV or SQ (weekly) |
| Cancer Protocols | 600 mg/m² | Single dose IV or SQ | |
| Cancer Protocols | 300 mg/m² per day | Continuous IV infusion over 48 hours | |
| Dogs | Granulomatous Meningoencephalomyelitis | 50 mg/m² twice daily | 2 days, repeated every 3 weeks SQ |
| Granulomatous Meningoencephalomyelitis | 200 mg/m² total dose | 50 mg/m² given four times over two days SQ or CRI | |
| Granulomatous Meningoencephalomyelitis | 25 mg/m² per hour | CRI for 8 hours | |
| Cats | Standard Protocol | 100 mg/m² once daily | 2 days |
Large Animal Dosage
| Species | Condition | Dosage | Frequency/Route |
|---|---|---|---|
| Large Animals | All Conditions | No dose reported | - |