Detomidine Hydrochloride Dosing for Dogs, Cats, Horses, Cattle, Calves By Weight
Important Safety Information
Higher oral mucosal doses in cats (2-4 mg/㎡) may cause vomiting. Reversal with 0.1 mg/kg atipamezole IM.
Use with caution in animals with cardiovascular disease. Monitor for bradycardia and hypotension.
Reference Source
Saunders Handbook of VETERINARY DRUGS, Page 243-244
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Standard Dosage Guidelines
Small Animal Dosage
| Species | Route | Dosage | Frequency |
|---|---|---|---|
| Dogs | IV | 5 mcg/kg (0.005 mg/kg) | Single dose |
| IM | 10-20 mcg/kg (0.01-0.02 mg/kg) | Single dose | |
| Oral Mucosal | 35 mcg/kg (0.035 mg/kg) average | Single dose | |
| Cats | Oral Mucosal | 0.5 mg/kg | Single dose |
Large Animal Dosage
| Species | Route | Dosage | Frequency |
|---|---|---|---|
| Horses | IV, IM | 10-40 mcg/kg (0.01-0.04 mg/kg) | Single dose |
| CRI | 10 mcg/kg bolus + infusion | Constant-rate infusion | |
| Oral Mucosal | 40 mcg/kg (0.04 mg/kg) | Single dose sublingual | |
| Cattle | IV | 2-10 mcg/kg (0.002-0.01 mg/kg) | Single dose |
| IM | 5-40 mcg/kg (0.005-0.04 mg/kg) | Single dose | |
| Calves | IV | 30 mcg/kg (0.03 mg/kg) | Single dose |
| Oral Mucosal | 80 mcg/kg (0.08 mg/kg) | Single dose |