Diltiazem Hydrochloride Dosing for Dogs, Cats, Horses By Weight
Important Safety Information
Extended-release tablets are not recommended for routine use in cats because they produce inconsistent plasma concentrations that may result in ineffective treatment in some and adverse effects in others.
Use with caution in animals with cardiovascular disease, hypotension, or liver impairment.
Reference Source
Saunders Handbook of VETERINARY DRUGS, Page 271-273
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Standard Dosage Guidelines
Small Animal Dosage
| Species | Route | Dosage | Frequency |
|---|---|---|---|
| Dogs | PO | 0.5-1.5 mg/kg | q8h |
| IV | 0.05-0.25 mg/kg | q5min to effect | |
| Cats | PO | 1.75-2.4 mg/kg | q8h |
| PO Extended-Release | 10 mg/kg | Once daily |
Large Animal Dosage
| Species | Route | Dosage | Frequency |
|---|---|---|---|
| Horses | IV | 0.125 mg/kg | Every 10 minutes as needed |
Special Considerations
- Dogs - Atrial Fibrillation: Doses as high as 5 mg/kg q12h PO have been used as monotherapy
- Dogs - Supraventricular Tachycardia: 0.25 mg/kg over 2 min IV (repeat if necessary)
- Dogs - Acute Renal Failure: 0.2 mg/kg IV (slowly), followed by 3-5 mcg/kg/min CRI
- Cats - Extended-Release: Use either Dilacor XR 30 or Dilacor XR 60. 30 mg per cat produces fewer adverse effects than 60 mg per cat
- Horses: Doses as high as 1-2 mg/kg have been used in research animals