Heparin Sodium Dosing for Dogs, Cats, Horses, Cattle, Pigs By Weight
Important Information
For heparinized saline solutions for IV use: recommended mixture ranges from 0.25 to 10 units per mL of fluids.
This is equivalent to adding 0.25 mL of heparin (1,000 units/mL concentration) per 1000 mL of fluids, or 1 mL heparin (10,000 units/mL concentration) per 1000 mL of fluids, respectively.
Note: The advantage of adding heparin to fluid solutions for flushing IV catheters has not been demonstrated in clinical studies.
Reference Source
Saunders Handbook of VETERINARY DRUGS, Page 401-403
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Standard Dosage Guidelines
Small Animal Dosage
| Species | Route | Dosage | Frequency |
|---|---|---|---|
| Dogs | SQ | 70 units/kg | q8-12h (Low-Dose Prophylaxis) |
| IV | 100-200 units/kg | Loading dose, then 100-300 units/kg q6-8h SQ | |
| SQ | 100-300 units/kg | q6-8h | |
| SQ | 500 units/kg | q12h (Severe cases) | |
| IV CRI | 18 units/kg/hour | After 100 units/kg IV loading dose | |
| Cats | SQ | 70 units/kg | q8-12h (Low-Dose Prophylaxis) |
| SQ | 300 units/kg | q8h | |
| SQ | 500 units/kg | q8h (if necessary) |
Large Animal Dosage
| Species | Route | Dosage | Frequency |
|---|---|---|---|
| Horses | SQ, IM | 125 units/kg | q8-12h |
| SQ | 80 units/kg | q12h | |
| Cattle | SQ, IM | 125 units/kg | q8-12h |
| Pigs | SQ, IM | 125 units/kg | q8-12h |
Heparinized Saline Preparation
| Concentration | Amount per 1000 mL fluids | Final Concentration |
|---|---|---|
| 1,000 units/mL | 0.25 mL | 0.25 units/mL |
| 10,000 units/mL | 1 mL | 10 units/mL |