Leucovorin Calcium Dosing for Dogs, Cats, and Horses
Important Safety Information
No large animal doses are reported. However, if pyrimethamine toxicosis is suspected in horses, doses listed for small animals may be considered.
Always monitor patient response and adjust dosage as needed based on clinical condition.
Reference Source
Saunders Handbook of VETERINARY DRUGS, Page 466-467
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Standard Dosage Guidelines
Small Animal Dosage
| Species | Purpose | Dosage | Route | Frequency |
|---|---|---|---|---|
| Dogs and Cats | With methotrexate administration | 3 mg/m² | IV, IM, or PO | As needed with methotrexate |
| Antidote for pyrimethamine toxicosis | 1 mg/kg | PO | Every 24 hours |
Large Animal Dosage
| Species | Purpose | Dosage | Route | Frequency |
|---|---|---|---|---|
| Horses | Antidote for pyrimethamine toxicosis | 1 mg/kg* | PO | Every 24 hours |
*No large animal doses are reported. However, if pyrimethamine toxicosis is suspected in horses, doses listed for small animals may be considered.