Methadone Hydrochloride Dosing for dogs, Cats, Horses By Weight
Important Safety Information
Oral mucosal administration in cats is approximately 2 times the IV dose because of less than 50% absorption.
Use with caution and monitor for respiratory depression, especially in animals with respiratory conditions.
Reference Source
Saunders Handbook of VETERINARY DRUGS, Page 529-530
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Standard Dosage Guidelines
Small Animal Dosage
| Species | Route | Dosage | Frequency |
|---|---|---|---|
| Dogs | IV | 0.1-0.5 mg/kg | Single dose |
| SQ, IM | 0.5-2.2 mg/kg | q3-4h | |
| Cats | IV, SQ, IM | 0.3-0.6 mg/kg | q3-4h |
Large Animal Dosage
| Species | Route | Dosage | Frequency |
|---|---|---|---|
| Horses | IV | 0.15 mg/kg | Single dose |
| Oral | 0.15 mg/kg | q6-8h |