Methylprednisolone Dosing for Dogs, Cats, Horses By Weight
Important Safety Information
Use with caution in animals with diabetes, heart disease, or gastrointestinal ulcers. Monitor for signs of Cushing's syndrome with long-term use.
Do not use in animals with systemic fungal infections. Taper dose gradually when discontinuing long-term therapy.
Reference Source
Saunders Handbook of VETERINARY DRUGS, Page 544-546
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Standard Dosage Guidelines
Small Animal Dosage
| Species | Route/Form | Dosage | Frequency |
|---|---|---|---|
| Dogs | PO (Methylprednisolone) | 0.22-0.44 mg/kg | q12-24h |
| IM (Acetate) | 1 mg/kg or 20-40 mg/dog | q1-3wk | |
| IV (Succinate - Emergency) | 30 mg/kg, repeat 15 mg/kg | Initial + 2-6 hours | |
| IV (Succinate - Therapy) | 0.25-0.5 mg/kg | Daily | |
| Cats | PO (Methylprednisolone) | 0.22-0.44 mg/kg | q12-24h |
| IM (Acetate) | 10-20 mg/cat | q1-3wk | |
| IV (Succinate - Emergency) | 30 mg/kg, repeat 15 mg/kg | Initial + 2-6 hours | |
| IV (Succinate - Therapy) | 0.25-0.5 mg/kg | Daily |
Large Animal Dosage
| Species | Route | Dosage | Frequency |
|---|---|---|---|
| Horses | IM | 200 mg total | Single dose |
| Intraarticular | 40-240 mg total | Single dose (average 120 mg) |