Mitotane Dosage Calculator

Mitotane Dosage for Dogs By Weight
Trade Names: Lysodren, op'-DDD
Functional classification: Adrenolytic agent

Mitotane Dosing for Dogs By Weight

Important Safety Information

Mitotane is specifically for canine use only. No large animal doses have been reported.

Monitor closely for signs of adrenal insufficiency during treatment. Use with caution and under veterinary supervision.

Reference Source

Saunders Handbook of VETERINARY DRUGS, Page 565-567

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Standard Dosage Guidelines

Small Animal Dosage

Species Condition Route Dosage Frequency Maintenance
Dogs PDH PO 50 mg/kg/day Daily in divided doses for 5-14 days 50-70 mg/kg/week PO
Adrenal tumor PO 50-75 mg/kg/day Daily for 10 days 75-100 mg/kg/week PO

Large Animal Dosage

Species Route Dosage Frequency
All large animals - No large animal doses reported -