Pergolide Mesylate Dosing for Horses and Small Animals By Weight
Important Safety Information
Small animal doses have not been established but have been extrapolated from human use. Start with 1 mcg/kg (0.001 mg/kg) daily PO and increase the dose gradually by 2 mcg/kg at a time until desired effects are observed.
For horses: Starting dose is 0.002 mg/kg (2 mcg/kg) q24h PO. After the starting dose, the dosage may be adjusted as needed (e.g., by 1-mcg/kg increments) to effect, up to 4 mcg/kg daily.
Reference Source
Saunders Handbook of VETERINARY DRUGS, Page 649-651
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Standard Dosage Guidelines
Small Animal Dosage
| Species | Route | Dosage | Frequency |
|---|---|---|---|
| Dogs | PO | 0.001 mg/kg (starting dose) | Once daily (increase gradually) |
| Cats | PO | 0.001 mg/kg (starting dose) | Once daily (increase gradually) |
Large Animal Dosage
| Species | Route | Dosage | Frequency |
|---|---|---|---|
| Horses | PO | 0.002-0.004 mg/kg | Once daily (may increase gradually) |
Dosage Adjustment Notes
Small Animals: Doses extrapolated from human use. Start with 1 mcg/kg (0.001 mg/kg) daily PO and increase gradually by 2 mcg/kg increments until desired effects are observed.
Horses: Starting dose: 0.002 mg/kg (2 mcg/kg) q24h PO (1 mg/day for 500-kg horse). Dosage may be adjusted as needed by 1-mcg/kg increments to effect, up to 4 mcg/kg daily, although a dose of 10 mcg/kg per day has been used in some horses.