Plicamycin Dosing for Dogs and Cats By Weight
Important Safety Information
Plicamycin is a potent anticancer agent with significant toxicity. Use with extreme caution and monitor hematological parameters closely.
Contraindicated in animals with bleeding disorders, thrombocytopenia, or renal impairment.
Reference Source
Saunders Handbook of VETERINARY DRUGS, Page 672-673
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Standard Dosage Guidelines
Small Animal Dosage
| Species | Indication | Dosage | Frequency | Administration |
|---|---|---|---|---|
| Dogs | Antihypercalcemic | 25 mcg/kg/day | Once daily | Slow IV infusion over 4 hours |
| Antineoplastic | 25-30 mcg/kg/day | Once daily for 8-10 days | Slow IV infusion | |
| Cats | Antihypercalcemic | 25 mcg/kg/day | Once daily | Slow IV infusion over 4 hours |
Large Animal Dosage
No doses have been reported for large animals.