Pralidoxime Chloride Dosing for Dogs, Cats, Cattle, Sheep, Pigs By Weight
Important Safety Information
Administer as a 10% solution. For IV administration, dilute solution in glucose and infuse slowly. Frequency can be assessed by monitoring clinical signs.
Use as an antidote for organophosphate poisoning in conjunction with atropine therapy.
Reference Source
Saunders Handbook of VETERINARY DRUGS, Page 689-690
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Standard Dosage Guidelines
Small Animal Dosage
| Species | Route | Dosage | Frequency |
|---|---|---|---|
| Dogs | IM, IV | 20-50 mg/kg | q8-12h |
| IV Note | Initial dose slow. Dilute in glucose and infuse slowly IV | ||
| Cats | IM, IV | 20-50 mg/kg | q8-12h |
| IV Note | Initial dose slow. Dilute in glucose and infuse slowly IV | ||
Large Animal Dosage
| Species | Route | Dosage | Frequency |
|---|---|---|---|
| Cattle | IM, IV | 20-50 mg/kg | q8h or as needed |
| Solution | Administered as a 10% solution | ||
| Sheep | IM, IV | 20-50 mg/kg | q8h or as needed |
| Solution | Administered as a 10% solution | ||
| Pigs | IM, IV | 20-50 mg/kg | q8h or as needed |
| Solution | Administered as a 10% solution | ||