Pyrimethamine Dosing for Dogs, Cats, Horses By Weight
Important Safety Information
For horses with EPM caused by Sarcocystis neurona, use in combination with a sulfonamide (see details on pyrimethamine + sulfadiazine).
For dogs with Neospora caninum, treatment duration is 5 days.
Reference Source
Saunders Handbook of VETERINARY DRUGS, Page 723-724
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Standard Dosage Guidelines
Small Animal Dosage
| Species | Route | Dosage | Frequency |
|---|---|---|---|
| Dogs | PO | 1 mg/kg | q24h for 14-21 days (5 days for Neospora caninum) |
| Cats | PO | 0.5-1 mg/kg | q24h for 14-28 days |
Large Animal Dosage
| Species | Route | Dosage | Frequency |
|---|---|---|---|
| Horses | PO | 1 mg/kg | q24h in combination with a sulfonamide (EPM caused by Sarcocystis neurona) |