Trilostane Dosing for Dogs, Cats, Horses By Weight
Important Safety Information
Adjust dose based on cortisol measurements. Large dogs (>30 kg) may require lower dose compared to small dogs (<15 kg).
Monitor for signs of hypoadrenocorticism and adjust dosage accordingly.
Reference Source
Saunders Handbook of VETERINARY DRUGS, Page 840-842
Weight Unit Converter ▲
Weight Unit Converter ▼
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Standard Dosage Guidelines
Small Animal Dosage
| Species | Dosage | Frequency | Notes |
|---|---|---|---|
| Dogs | 3-6 mg/kg | Once daily PO | Adjust based on cortisol measurements |
| 1.5-3 mg/kg | q12h PO | Many dogs are controlled with lower dose | |
| Weight-based schedule | q24h PO | 4.5-10 kg: 30 mg, 10-20 kg: 60 mg, 20-40 kg: 120 mg, 40-60 kg: 180 mg | |
| 9-12 mg/kg | Daily PO | Treatment of alopecia X | |
| Cats | 3-6 mg/kg | q24h PO | Gradually increase to 10 mg/kg as needed |
| 3 mg/kg | q12h PO | Some cats better controlled with twice-daily administration |
Large Animal Dosage
| Species | Dosage | Frequency | Notes |
|---|---|---|---|
| Horses | 0.4-1 mg/kg | Daily PO | Added to feed |