Trimethoprim Sulfadiazine Dosing for Dogs, Cats, Horses, Cattle By Weight
Important Safety Information
Doses are listed as the combined sulfonamide + trimethoprim.
Trimethoprim is not absorbed orally in ruminants, but it is absorbed in calves.
Use with caution in animals with liver or kidney impairment.
Reference Source
Saunders Handbook of VETERINARY DRUGS, Page 845-847
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Standard Dosage Guidelines
Small Animal Dosage
| Species | Route | Dosage | Frequency | Notes |
|---|---|---|---|---|
| Dogs | PO | 15-30 mg/kg | q12h | Combined drug |
| PO | 30 mg/kg | q12h | Toxoplasma treatment | |
| Cats | PO | 15-30 mg/kg | q12h | Combined drug |
| PO | 30 mg/kg | q12h | Toxoplasma treatment |
Large Animal Dosage
| Species | Route | Dosage | Frequency | Notes |
|---|---|---|---|---|
| Horses | PO | 24-30 mg/kg | q12h | 10 days treatment |
| Cattle | IV, IM | 16 mg/kg | q24h | Trimethoprim + sulfadoxine |