Valproic Acid, Valproate Sodium Dosing for Dogs By Weight
Important Safety Information
Dose not established for cats. No dose has been reported for large animals.
Use with caution and monitor liver function during treatment.
Reference Source
Saunders Handbook of VETERINARY DRUGS, Page 859-860
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Standard Dosage Guidelines
Small Animal Dosage
| Species | Route | Dosage | Frequency |
|---|---|---|---|
| Dogs | PO | 50-250 mg per dog | q8h |
| PO (Delayed-release) | 250-500 mg per dog | q12h | |
| Cats | - | Dose not established | - |
Large Animal Dosage
| Species | Route | Dosage | Frequency |
|---|---|---|---|
| Horses | - | No dose reported | - |
| Cattle | - | No dose reported | - |
| Pigs | - | No dose reported | - |
Additional Information
Delayed-release formulations: Start with 250 mg per dog q12h PO and increase to 500 mg per dog q12h as needed.
Drug interactions: Higher doses should be used if dogs are also receiving phenobarbital.