Xylazine Hydrochloride Dosing for dogs, Cats, Horses, Pigs, Cattle, Sheep, Goats By Weight
Important Safety Information
For pigs: Use in combination with other drugs in swine (e.g., 2 mg/kg xylazine + 10 mg/kg ketamine, administered IM). Unreliable alone.
For horses: For anesthesia purposes, it is sometimes combined with other agents such as ketamine and guaifenesin in the equine "triple-drip" combination.
Use with caution and monitor cardiovascular parameters.
Reference Source
Saunders Handbook of VETERINARY DRUGS, Page 877-879
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Standard Dosage Guidelines
Small Animal Dosage
| Species | Route | Dosage | Frequency |
|---|---|---|---|
| Dogs | IV | 1.1 mg/kg | Single dose |
| IM | 2.2 mg/kg | Single dose | |
| IM, IV, SQ | 0.1-0.5 mg/kg | Short-term treatment of pain | |
| Cats | IM | 1.1 mg/kg | Single dose |
| IM, IV | 0.4-0.5 mg/kg | Emetic dose | |
| IM, IV, SQ | 0.1-0.5 mg/kg | Short-term treatment of pain |
Large Animal Dosage
| Species | Route | Dosage | Frequency |
|---|---|---|---|
| Horses | IM | 1-2 mg/kg | Single dose |
| IV | 0.5-1.0 mg/kg | Standing chemical restraint | |
| IV (CRI) | 0.72 mg/kg/hour | Constant-rate infusion | |
| IV (Colic) | 0.3-0.5 mg/kg | For colic pain | |
| Cattle | IM | 0.1-0.2 mg/kg | Single dose |
| IV | 0.03-0.1 mg/kg | Single dose | |
| Pigs | IM | 0.5-3 mg/kg | Use in combination with other drugs |
| Sheep | IM | 0.1-0.3 mg/kg | Single dose |
| IV | 0.05-0.1 mg/kg | Single dose | |
| Goats | IM | 0.05-0.5 mg/kg | Single dose |
| IV | 0.01-0.5 mg/kg | Single dose |